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Phenacetin Basic information
Chemical drugs, antipyretic and analgesic drugs, antiviral drugs, anti-inflammatory drugs, pharmaceutical chemical raw materials, botanicals

Antipyretic analgesic, used for the treatment of fever, headache, neuralgia, etc.
Antipyretic effect is stronger than analgesic effect.
The efficacy intensity is similar to that of aspirin, the effect is slow and lasting, and the toxicity is low.
The study shows that this product and its metabolite paracetamol have antipyretic effect.
Because the enzyme inhibitors of phenacetin can not be converted to paracetamol, can still show a significant antipyretic effect.
Therefore, the antipyretic effect of the raw material was not only caused by its active product, acetaminophen.
The mild analgesic effect of finacetin is generally maintained for 3-4 hours.
The synergistic effect with salicylic acid can enhance the analgesic effect.
Clinically, it is mainly used for antipyretic analgesia of small animals.
It is also a component of APC Tablets.
Chemical Properties Uses Indications and Usage Mechanisms of Action Side Effects Carcinogenicity Synthesis of Phenacetin
Product Name: Phenacetin
CAS: 62-44-2
MF: C10H13NO2
MW: 179.22
EINECS: 200-533-0
Product Categories: Others;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;organic interme;API;Other APIs;Organics
Mol File: 62-44-2.mol
Phenacetin Structure
Phenacetin Chemical Properties
Melting point 133-136 °C(lit.)
Boiling point 132 °C / 4mmHg
density 1.1248 (rough estimate)
refractive index 1.5710
Fp 2℃
storage temp. 2-8°C
pka pKa 2.2(H2O) (Uncertain);3.5(aqueous acetone) (Uncertain)
form powder
color White
Water Solubility 0.076 g/100 mL
Sensitive Hygroscopic
Merck 14,7204
BRN 1869238
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.

Listing ID: 50160b721e487935